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Resumen de Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin

Gabriela Whelan, Emanuel Kreidl, Gordana Wutz, Alexander Egner, Jan-Michael Peters, Gregor Eichele

  • Genetic deletion of murine Esco2 (an acetylase known to establish cohesin during S-phase and genetically linked to Roberts syndrome) results in embryonic lethality that can be molecularly linked to novel and specific functions of Esco2 at pericentric heterochromatin.


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