25(OH) Vitamin D Is Associated with Greater Muscle Strength in Healthy Men and Women.

• Autores: Adam S. Grimaldi, Paul D. Thompson, Beth A. Parker, Michael C. White, Jeffrey A. Capizzi, Linda S. Pescatello, Priscilla M. Clarkson
• Localización: Medicine & Science in Sports & exercise: Official Journal of the American College of Sports Medicine, ISSN 0195-9131, Vol. 45, Nº. 1, 2013, págs. 157-162
• Idioma: inglés
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• Dialnet Métricas: 2 Citas
• Resumen

  • AB Purpose: The purpose of the study was to examine the relation between serum 25-hydroxy vitamin D (25(OH)D) levels and muscle strength in 419 healthy men and women over a broad age range (20-76 yr). Methods: Isometric and isokinetic strength of the arms and legs was measured using computerized dynamometry, and its relation to vitamin D was tested in multivariate models controlling for age, gender, resting HR, systolic blood pressure, diastolic blood pressure, body mass index, maximal oxygen uptake (V[spacing dot above]O2max,), physical activity counts, and season of vitamin D measurement. Results: Vitamin D was significantly associated with arm and leg muscle strength when controlling for age and gender. When controlling for other covariates listed previously, vitamin D remained directly related to both isometric and isokinetic arm strength but only to isometric leg strength. Conclusion: These data suggest that there may be a differential effect of vitamin D on upper and lower body strength. The mechanism for this difference remains unclear but could be related to differences in androgenic effects or to differences in vitamin D receptor expression. Our study supports a direct relation between vitamin D and muscle strength and suggests that vitamin D supplementation be evaluated to determine whether it is an effective therapy to preserve muscle strength in adults.