Regulated cell death in diagnostic histopathology

• Faruk Skenderi ^[1] ; Semir Vranic ^[1] ; Ivan Damjanov ^[2]
  1. [1] University of Sarajevo

     University of Sarajevo

     Bosnia y Herzegovina

     
  2. [2] University of Kansas

     University of Kansas

     City of Lawrence, Estados Unidos

     
• Localización: International journal of developmental biology, ISSN 0214-6282, Vol. 59, Nº. Extra 1-3, 2015 (Ejemplar dedicado a: Cell Death in Development & Tumors), págs. 149-158
• Idioma: inglés
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• Resumen

  • Regulated cell death (RCD) is a controlled cellular process, essential for normal development, tissue integrity and homeostasis, and its dysregulation has been implicated in the pathogenesis of various conditions including developmental and immunological disorders, neurodegenerative diseases, and cancer. In this review, we briefly discuss the historical perspective and conceptual development of RCD, we overview recent classifications and some of the key players in RCD; finally we focus on current applications of RCD in diagnostic histopathology.