Valoración de la adherencia al tratamiento antirretroviral. Análisis de factores relacionados

• Autores: José Manuel Real Campaña, Herminia Navarro Aznárez, C. Lapresta, María José Rabanaque Hernández, Elisa Soler Giner
• Localización: Atención Farmacéutica, ISSN 1139-7357, Vol. 13, Nº. 4, 2011, págs. 215-221
• Idioma: español
• Títulos paralelos:
  • Evaluation of adherence to antiretroviral treatment. Analysis of related factors
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• Resumen

  • Objectives: To learn about HIV patients' adherence to antiretroviral treatment (ART), its relation to treatment effectiveness and the influence of different factors on it. Method: Cross-sectional study on adherence analysis by using two indirect methods: SMAQ (Simplified Medication Adherence Questionnaire) questionnaire and the Pharmacy Department's medical dispensation record (MDR). We conducted a retrospective analytical study for determining the influence of various factors on adherence. Results: 252 patients were included in the study. Adherence according to the MDR was 77.6% and according to SMAQ of 56%. We found a relation between adherence and viral load based on the MDR (p < 0.05). In the logistic regression according to the MDR, the following factors were able to explain adherence: age, immunological status, being polymedicated with more than 3 drugs, and tobacco and alcohol consumption. Conclusions: We observe a direct relation between adherence and therapeutic success. There is evidence of a relation between low adherence and being polymedicated with more than 3 drugs (p < 0.05)