Alfa, fetoproteina en neonatología en neonatología:: Valoración de la edad gestacional y en el síndrome de dificultad respiratoria idiopático

• Autores: J. L. Madrazo, J. López, María Carmen González Vela, Enrique Casado de Frías
• Localización: Anales españoles de pediatría: Publicación oficial de la Asociación Española de Pediatría ( AEP ), ISSN 0302-4342, Vol. 9, Nº. 2, 1976, págs. 121-129
• Idioma: español
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• Resumen

  • Cord serum AFP levels were determined in 66 newborn samples between 30 to 42 wk of gestational age. Results showed some relation between AFP rate and newborn maturity degree, so it was possible to predict the gestational age with some limits of error ± 17 days in full term newborns, and ± 10 days in premature ones. Quantification in the amniotic fluid of 18 high risk gestations gave normal AFP rates. point of 30 patients with respiratory distress was tested. An AFP increase was present in 14 of 15 cases of hyaline membrane. In the remaining 15 cases of respiratory distress only 3 gave high levels. These facts show that AFP can be used as a suitable parameter in the biochemical diagnosis of hyaline membrane.