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| Título: | Antigen receptor signaling competence and the determination of B cell fate in B-lymphopoiesis |
| Fecha de publicación: | 2005 |
| Editorial: | Murcia : F. Hernández |
| ISSN: | 0213-3911 |
| Materias relacionadas: | CDU::6 - Ciencias aplicadas::61 - Medicina |
| Palabras clave: | Negative selection Receptor editing |
| Resumen: | Recent studies suggest that developmental check-points in B-lymphopoiesis are set in order to test the B cell receptor signaling competence. In these checkpoints ligand-independent and ligand-dependent receptor signals confer B-lymphopoiesis with positive and negative selection events. As a consequence, Blymphocytes are forced to make crucial fate decisions to determine developmental progression, survival or apoptosis. In here we review recent progress in unraveling molecular and cellular mechanisms for the role of B cell receptor signaling competence in determination of the B cell fate. |
| Autor/es principal/es: | Keren, Z. Melamed, D. |
| Forma parte de: | Histology and histopathology |
| URI: | http://hdl.handle.net/10201/22443 |
| Tipo de documento: | info:eu-repo/semantics/article |
| Número páginas / Extensión: | 10 |
| Derechos: | info:eu-repo/semantics/openAccess |
| Aparece en las colecciones: | Vol.20, nº 1 (2005) |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| Antigen receptor signaling competence and the.pdf | 4,99 MB | Adobe PDF |  Visualizar/Abrir |
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