Publication: Valoración del volumen hepático mediante Tomografía Computarizada en la predicción de la hipertensión portal clínicamente significativa en pacientes con cirrosis compensada
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2021-08-19
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Universidad Complutense de Madrid
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Abstract
El grado de hipertensión portal es el factor pronóstico más importante en la enfermedad hepática avanzada compensada. Clasifica los pacientes entre aquéllos que presentan o no riesgo de descompensación en función de la existencia o ausencia de hipertensión portal clínicamente significativa (HPCS). Del mismo modo, aunque no existe una relación tan inequívoca, los pacientes con hipertensión portal podrían presentar un riesgo superior de desarrollar carcinoma hepatocelular independientemente del tiempo de evolución de la enfermedad y de la gravedad de la cirrosis. En la práctica clínica, el método para el diagnóstico y la cuantificación del grado de hipertensión portal es elcateterismo de las venas suprahepáticas para medir el gradiente de presión venosa hepática (GPVH). Es bien conocido, en resumen, que los pacientes con hipertensión portal clínicamente significativa presentan riesgo de desarrollar varices esofágicas y descompensación de la enfermedad, tanto más probable cuanto mayor sea el gradiente de presión venosa hepática...
The degree of portal hypertension is the most important prognostic factor in compensated advanced liver disease. It classifies patients among those with or without risk of decompensation based on the existence or absence of clinically significant portal hypertension. Alike, although such an unequivocal relationship does not exist, patients with portal hypertension could present a higher risk of developing hepatocellular carcinoma regardless of the evolution time of the disease as well as the severity of cirrhosis. In clinical practice, the method to diagnose and determine the degree of portal hypertension is the catheterization of the suprahepatic veins to measure the hepatic venous pressure gradient. To summarize, it is well known that patients with clinically significant portal hypertension are at risk of developing esophageal varices and decompensation of the disease...
The degree of portal hypertension is the most important prognostic factor in compensated advanced liver disease. It classifies patients among those with or without risk of decompensation based on the existence or absence of clinically significant portal hypertension. Alike, although such an unequivocal relationship does not exist, patients with portal hypertension could present a higher risk of developing hepatocellular carcinoma regardless of the evolution time of the disease as well as the severity of cirrhosis. In clinical practice, the method to diagnose and determine the degree of portal hypertension is the catheterization of the suprahepatic veins to measure the hepatic venous pressure gradient. To summarize, it is well known that patients with clinically significant portal hypertension are at risk of developing esophageal varices and decompensation of the disease...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, leída el 07-07-2021