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Comparative Study of Two Root Coverage Procedures: A 24-Month Follow-Up Multicenter Study

  • Autores: Georgios E. Romanos, Carlos E. Nemcovsky, Ofer Moses, Zvi Artzi, Anton Sculean, Haim Tal, Avital Kozlovsky
  • Localización: Journal of periodontology, ISSN 0022-3492, Vol. 77, Nº. 2, 2006, págs. 195-202
  • Idioma: inglés
  • Texto completo no disponible (Saber más ...)
  • Resumen
    • Comparative Study of Two Root Coverage Procedures: A 24-Month Follow-Up Multicenter Study Ofer Moses,* Zvi Artzi,* Anton Sculean,† Haim Tal,* Avital Kozlovsky,* Georgios E. Romanos,‡ and Carlos E. Nemcovsky*§ *Department of Periodontology, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel.

      †Department of Periodontology, Radboud University Medical Center, Nijmegen, The Netherlands.

      ‡Department of Implant Dentistry, College of Dentistry, New York University, New York, NY.

      §Dental and Maxillofacial Center, Souraski Tel-Aviv Medical Center, Tel-Aviv, Israel.

      Correspondence: Dr. Carlos E. Nemcovsky, Department of Periodontology, School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel. Fax: 972-3-6409250; e-mail: carlos@post.tau.ac.il.

      Background: Treatment alternatives to cover exposed root surfaces include free grafts, pedicle flaps, and barrier membranes. This 24-month follow-up study clinically evaluated the long-term effect of a coronally advanced flap procedure with the additional use of enamel matrix derivative (EMD) to treat gingival recession versus the subpedicle connective tissue graft (CTG) procedure.

      Methods: Miller Class I or II buccal recession-type defects in the anterior teeth or premolars in 65 patients (28 in EMD and 37 in CTG groups) were treated in several centers. At baseline and 12 and 24 months post-treatment, vertical recession defect (VRD), height of keratinized tissue (HKT), and probing depth (PD) were recorded, and the percentage of root coverage (PRC) of the original defect was calculated. Student t test, analysis of variance, and analysis of covariance were used for statistical analyses.

      Results: At 12- and 24-month evaluations, PRC was 73.2% (SD = 15.58%) and 76.9% (SD = 16.77%) in the EMD group and 86.8% (SD = 12.48%) and 84.3% (SD = 13.32%) in the CTG group, respectively (P <0.001). Differences between groups were statistically significant (P = 0.002). Baseline HKT was 1.07 mm (SD = 0.66 mm) in the EMD group and 1.65 mm (SD = 0.92 mm) in the CTG group. At 12 and 24 months, values were 1.75 mm (SD = 0.59 mm) and 2.25 mm (SD = 0.52 mm) in the EMD group and 4.24 mm (SD = 0.89 mm) and 4.05 mm (SD = 0.94 mm) in the CTG group, respectively. Differences in HKT were statistically significant within (EMD: P <0.001; CTG: P = 0.017) and between (P <0.001) groups.

      Conclusions: Both treatments proved clinically successful. CTG treatment showed a higher percentage of root coverage and HKT increase. EMD is a valuable, long-term effective treatment alternative to achieve root coverage together with an increase in HKT.

      KEYWORDS: Enamel matrix proteins, gingival recession/surgery, surgical flaps, tooth Cited by G.-L. Cheng, E. Fu, Y.-K. Tu, E.-C. Shen, H.-C. Chiu, R.-Y. Huang, D.-Y. Yuh and C.-Y. Chiang. (2015) Root coverage by coronally advanced flap with connective tissue graft and/or enamel matrix derivative: a meta-analysis. Journal of Periodontal Research 50:10.1111/jre.2015.50.issue-2, 220-230.

      Online publication date: 1-Apr-2015.

      CrossRef Leandro Chambrone and Dimitris N. Tatakis. (2015) Periodontal Soft Tissue Root Coverage Procedures: A Systematic Review From the AAP Regeneration Workshop. Journal of Periodontology 86:2-s, S8-S51.

      Online publication date: 1-Feb-2015.

      Abstract | Full Text | PDF (2699 KB) | PDF Plus (1472 KB) Gülnihal Eren and Gül Atilla. (2014) Platelet-rich fibrin in the treatment of localized gingival recessions: a split-mouth randomized clinical trial. Clinical Oral Investigations 18, 1941-1948.

      Online publication date: 1-Nov-2014.

      CrossRef A. Roman, A. Soancă, A. Kasaj and S.-I. Stratul. (2013) Subepithelial connective tissue graft with or without enamel matrix derivative for the treatment of Miller class I and II gingival recessions: a controlled randomized clinical trial. Journal of Periodontal Research 48:10.1111/jre.2013.48.issue-5, 563-572.

      Online publication date: 1-Oct-2013.

      CrossRef Guido Rhemrev. (2013) Postoperatieve zorg na parodontale chirurgie. Tandartspraktijk 34, 34-37.

      Online publication date: 1-Mar-2013.

      CrossRef Christopher Bates, Victor Marino, Nicola L. Fazzalari and P. Mark Bartold. (2013) Soft Tissue Attachment to Titanium Implants Coated with Growth Factors. Clinical Implant Dentistry and Related Research 15:10.1111/cid.2013.15.issue-1, 53-63.

      Online publication date: 1-Feb-2013.

      CrossRef Elizabeth P. Rosetti, Elcio Marcantonio, Elizangela P. Zuza and Rosemary A.C. Marcantonio. (2013) Root coverage stability of the subepithelial connective tissue graft and guided tissue regeneration: A 30-month follow-up clinical trial. Journal of Dentistry 41, 114-120.

      Online publication date: 1-Feb-2013.

      CrossRef N. Donos, X Dereka and H.D. Amin. 2013. Enamel matrix proteins (EMP) for periodontal regeneration. Non-Metallic Biomaterials for Tooth Repair and Replacement, 90-125.

      CrossRef Michael K. McGuire, E. Todd Scheyer and Martha Nunn. (2012) Evaluation of Human Recession Defects Treated With Coronally Advanced Flaps and Either Enamel Matrix Derivative or Connective Tissue: Comparison of Clinical Parameters at 10 Years. Journal of Periodontology 83:11, 1353-1362.

      Online publication date: 1-Nov-2012.

      Abstract | Full Text | PDF (1617 KB) | PDF Plus (671 KB) Gülnihal Eren and Gül Atilla. (2012) Platelet-Rich Fibrin in the Treatment of Bilateral Gingival Recessions. Clinical Advances in Periodontics 2:3, 154-160.

      Online publication date: 1-Aug-2012.

      Abstract | Full Text | PDF (2118 KB) | PDF Plus (770 KB) Richard Koop, Joe Merheb and Marc Quirynen. (2012) Periodontal Regeneration With Enamel Matrix Derivative in Reconstructive Periodontal Therapy: A Systematic Review. Journal of Periodontology 83:6, 707-720.

      Online publication date: 1-Jun-2012.

      Abstract | Full Text | PDF (1377 KB) | PDF Plus (839 KB) Neda Moslemi, Mahvash Mousavi Jazi, Farideh Haghighati, Seyyedeh Pouya Morovati and Raika Jamali. (2011) Acellular dermal matrix allograft versus subepithelial connective tissue graft in treatment of gingival recessions: a 5-year randomized clinical study. Journal of Clinical Periodontology 38:10.1111/jcpe.2011.38.issue-12, 1122-1129.

      Online publication date: 1-Dec-2011.

      CrossRef Seda Ozturan, Sulhi Andac Durukan, Onur Ozcelik, Gulsah Seydaoglu and Mehmet Cenk Haytac. (2011) Coronally advanced flap adjunct with low intensity laser therapy: a randomized controlled clinical pilot study. Journal of Clinical Periodontology 38:10.1111/jcpe.2011.38.issue-11, 1055-1062.

      Online publication date: 1-Nov-2011.

      CrossRef Anton Sculean, Regina Alessandri, Richard Miron, Giovanni E. Salvi and Dieter D. Bosshardt. (2011) Enamel Matrix Proteins and Periodontal Wound Healing and Regeneration. Clinical Advances in Periodontics 1:2, 101-117.

      Online publication date: 1-Aug-2011.

      Abstract | Full Text | PDF (4173 KB) | PDF Plus (1317 KB) Patrícia F. Andrade, Márcio F.M. Grisi, Andrea M. Marcaccini, Patrícia G. Fernandes, Danilo M. Reino, Sérgio L.S. Souza, Mário Taba , Jr., Daniela B. Palioto and Arthur B. Novaes , Jr.. (2010) Comparison Between Micro- and Macrosurgical Techniques for the Treatment of Localized Gingival Recessions Using Coronally Positioned Flaps and Enamel Matrix Derivative. Journal of Periodontology 81:11, 1572-1579.

      Online publication date: 1-Nov-2010.

      Abstract | Full Text | PDF (1454 KB) | PDF Plus (634 KB) Leandro Chambrone, Flávia Sukekava, Maurício G. Araújo, Francisco E. Pustiglioni, Luiz Armando Chambrone and Luiz A. Lima. (2010) Root-Coverage Procedures for the Treatment of Localized Recession-Type Defects: A Cochrane Systematic Review. Journal of Periodontology 81:4, 452-478.

      Online publication date: 1-Apr-2010.

      Abstract | Full Text | PDF (937 KB) | PDF Plus (854 KB) Paulo S. G. Henriques, André A. Pelegrine, Ana A. Nogueira and Mônica M. Borghi. (2010) Application of subepithelial connective tissue graft with or without enamel matrix derivative for root coverage: a split-mouth randomized study. Journal of Oral Science 52, 463-471.

      Online publication date: 1-Jan-2010.

      CrossRef Sofia Aroca, Tibor Keglevich, Dimitris Nikolidakis, Istvan Gera, Katalin Nagy, Robert Azzi and Daniel Etienne. (2010) Treatment of class III multiple gingival recessions: a randomized-clinical trial. Journal of Clinical Periodontology 37:10.1111/cpe.2010.37.issue-1, 88-97.

      Online publication date: 1-Jan-2010.

      CrossRef Sandro Bittencourt, Érica Del Peloso Ribeiro, Enilson A. Sallum, Antônio W. Sallum, Francisco H. Nociti , Jr. and Márcio Zaffalon Casati. (2009) Semilunar Coronally Positioned Flap or Subepithelial Connective Tissue Graft for the Treatment of Gingival Recession: A 30-Month Follow-Up Study. Journal of Periodontology 80:7, 1076-1082.

      Online publication date: 1-Jul-2009.

      Abstract | Full Text | PDF (907 KB) | PDF Plus (569 KB) Leandro Chambrone, Flávia Sukekava, Maurício G Araújo, Francisco E Pustiglioni, Luiz Armando Chambrone, Luiz A Lima and Leandro Chambrone. 2009. Root coverage procedures for the treatment of localised recession-type defects. Cochrane Database of Systematic Reviews.

      CrossRef L. Chambrone, D. Chambrone, F. E. Pustiglioni, L. A. Chambrone and L. A. Lima. (2009) The Influence of Tobacco Smoking on the Outcomes Achieved by Root-Coverage Procedures: A Systematic Review. Journal of the American Dental Association 140, 294-306.

      Online publication date: 1-Mar-2009.

      CrossRef Leandro Chambrone, Daniela Chambrone, Francisco E. Pustiglioni, Luiz A. Chambrone and Luiz A. Lima. (2008) Can subepithelial connective tissue grafts be considered the gold standard procedure in the treatment of Miller Class I and II recession-type defects?. Journal of Dentistry 36, 659-671.

      Online publication date: 1-Sep-2008.

      CrossRef Francesco Cairo, Umberto Pagliaro and Michele Nieri. (2008) Treatment of gingival recession with coronally advanced flap procedures: a systematic review. Journal of Clinical Periodontology 35:10.1111/cpe.2008.35.issue-s8, 136-162.

      Online publication date: 1-Sep-2008.

      CrossRef Denise C. Andia, Ângela G. Martins, Márcio Z. Casati, Enilson A. Sallum and Francisco H. Nociti , Jr.. (2008) Root Coverage Outcome May Be Affected by Heavy Smoking: A 2-Year Follow-Up Study. Journal of Periodontology 79:4, 647-653.

      Online publication date: 1-Apr-2008.

      Abstract | Full Text | PDF (793 KB) | PDF Plus (579 KB) Stéphane Kerner, Alain Borghetti, Sandrine Katsahian, Daniel Etienne, Jacques Malet, Francis Mora, Virginie Monnet-Corti, Jean-Marc Glise and Philippe Bouchard. (2008) A Retrospective study of root coverage procedures using an image analysis system. Journal of Clinical Periodontology 35, 346-355.

      Online publication date: 1-Apr-2008.


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