RC_Link: Genetic linkage analysis using Bayesian networks

• Autores: David Allen, Adnan Darwiche
• Localización: International journal of approximate reasoning, ISSN 0888-613X, Vol. 48, Nº 2, 2008 , págs. 499-525
• Resumen

  • Genetic linkage analysis is a statistical method for mapping genes onto chromosomes, and is useful for detecting and predicting diseases. One of its current limitations is the computational complexity of the problems of interest. This research presents methods for mapping genetic linkage problems as Bayesian networks and then addresses novel techniques for making the problems more tractable. The result is a new tool for solving these problems called RC_Link, which in many cases is orders of magnitude faster than existing tools