El cerebelo: su implicación en la dislexia

Autores/as

  • Angela Fawcett Departamento de Psicología, Universidad de Sheffield
  • Rod Nicolson Departamento de Psicología, Universidad de Sheffield

DOI:

https://doi.org/10.25115/ejrep.v2i4.1149

Palabras clave:

Dislexia, cerebelo, fonología, cadena causal.

Resumen

Introducción: En esta revisión exponemos, en líneas generales, el razonamiento y la evidencia que respalda nuestra hipótesis que los problemas sufridos por los disléxicos pueden atribuirse a un deficit cerebelar.

Método: Primero, ofrecemos una perspectiva general de la evidencia reciente que propone un papel importante del cerebelo en las habilidades cognitivas, particularmente las que apoyan el lenguaje hablado, además de su papel ya reconocido en las habilidades motrices. Segundo, resumimos la evidencia de nuestro laboratorio a favor de que la función cerebelar sea anormal en la dislexia.

Resultados: Consideramos dos líneas concretas de evidencia: la conductual, y la evidencia convergent de la neuroimagen, la cual demuestra diferencias significativas entre los grupos disléxicos y de control. También administramos la misma batería de pruebas conductuales a un grupo de niños que son malos lectores no discrepantes.

Discusión: Finalmente, proponemos una cadena causal ontogenético para el desarrollo de la dislexia como déficit cerebelar desde el nacimiento, considerando las implicaciones de este marco para las cuestiones clave en la investigación sobre la dislexia.

Descargas

Los datos de descargas todavía no están disponibles.

Citas

Ackermann, H., & Hertrich, I. (2000). The contribution of the cerebellum to speech process-ing. Journal of Neurolinguistics, 13(2-3), 95-116.

Ackermann, H., Wildgruber, D., Daum, I., & Grodd, W. (1998). Does the cerebellum contrib-ute to cognitive aspects of speech production? A functional magnetic resonance imaging (fMRI) study in humans. Neuroscience Letters, 247, 187-190.

Bates, E., & Dick, F. (2002). Language, gesture, and the developing brain. Developmental Psychobiology, 40(3), 293-310

Bower, J.M. and Parsons, L.M. (2003). Rethinking the lesser brain. Scientific American, 289,50-57.

Coffin, J. M., Baroody, S., Schneider, K and JO’Neill, J. (2003 in press). Impaired Cerebellar Learning In Children With Prenatal Alcohol Exposure: A Comparative Study of Eye-blink Conditioning In Children with ADHD Cortex,in press.

Cohen, J. (1969). Statistical power analysis for the behavioural sciences. New York: Aca-demic Press.

Daum I, Schugens MM, Ackermann H, Lutzenberger W, Dichgans J, Birbaumer N (1993) Classical Conditioning after cerebellar lesions in humans. Behavioral Neuroscience 107: 748-756.

Dow, R. S., & Moruzzi, G. (1958). The physiology and pathology of the cerebellum. Minnea-polis: University of Minnesota Press.

Eckert, M. A., Leonard, C. M., Richards, T., Aylward, E., Thomson, J., & Berninger, V. (2002, in press). Anatomical Correlates of Dyslexia: Frontal and Cerebellar Findings. Brain.

Eccles, J. C., Ito, M., & Szentagothai, J. (1967). The cerebellum as a neuronal machine. New York: Springer-Verlag.

Ejiri, K., & Masataka, N. (2001). Co-occurrence of preverbal vocal behavior and motor action in early infancy. Developmental Science, 4(1), 40-48.

Fabbro, F., Moretti, R., & Bava, A. (2000). Language impairments in patients with cerebellar lesions. Journal of Neurolinguistics, 13(2-3), 173-188.

Facoetti, A., Turatto, M., Lorusso, M. L., Mascetti, G.G., (2001). Orienting of visual attention in dyslexia: evidence for asymmetric hemispheric control of attention. Experimental Brain Research 138, 46-53

Facoetti, A., Lorusso, M. L., Paganoni, P., Cattaneo, C., Galli, R., Umilta, C., & Mascetti, G. G. (2003). Auditory and visual automatic attention deficits in developmental dyslexia. Brain Res Cogn Brain Res, 16(2), 185-191

Fawcett, A. J., & Nicolson, R. I. (1994). Naming speed in children with dyslexia. Journal of Learning Disabilities, 27, 641-646.

Fawcett, A. J., & Nicolson, R. I. (1995a). Persistence of phonological awareness deficits in older children with dyslexia. Reading and Writing, 7, 361-376.

Fawcett, A. J. and Nicolson, R. I. (1995b). Persistent deficits in motor skill for children with dyslexia. Journal of Motor Behaviour. 27, 235-240

Fawcett, A. J., & Nicolson, R. I. (1999). Performance of dyslexic children on cerebellar and cognitive tests. Journal of Motor Behaviour, 31, 68-78.

Fawcett, A. J., Nicolson, R. I., & Dean, P. (1996). Impaired performance of children with dyslexia on a range of cerebellar tasks. Annals of Dyslexia, 46, 259-283.

Finch, A. J., Nicolson, R. I., & Fawcett, A. J. (2002). Evidence for a neuroanatomical difference within the olivo-cerebellar pathway of adults with dyslexia. Cortex, 38(4), 529-539..

Frank, J., & Levinson, H. N. (1973). Dysmetric dyslexia and dyspraxia: hypothesis and study. Journal of American Academy of Child Psychiatry, 12., 690-701.

Fulbright, R. K., Jenner, A. R., Mencl, W. E., Pugh, K. R., Shaywitz, B. A., Shaywitz, S. E., Frost, S. J., Skudlarski, P., Constable, R. T., Lacadie, C. M., Marchione, K. E., & Gore, J. C. (1999). The cerebellum's role in reading: A functional MR imaging study. American Journal of Neuroradiology, 20, 1925-1930.

Gebhart, A. L., Petersen, S.E. and Thach, W. T., (2002). Role of the posterolateral cerebellum in language. In Highstein and Thach (Eds.). The Cerebellum: Recent developments in cerebellar research: (Special Issue of the Annals of the New York Academy of Sci-ences), 978, 318-333.

Glickstein, M. (1993). Motor skills but not cognitive tasks. Trends in Neuroscience, 16, 450-451.

Hanakawa, T., Honda, M., Sawamoto, N., Okada, T., Yonekura, Y., Fukuyama, H., and Shi-basaki, H. (2002). The role of Rostral Brodmann Area 6 in Mental Operation tasks: an integrative neuroimaging approach. Cerebral Cortex, 12, 1157-1170.

Holmes, G. (1917). The symptoms of acute cerebellar injuries due to gunshot injuries. Brain, 40, 461-535.

Holmes, G. (1922). Clinical symptoms of cerebellar disease and their interpretation. Lancet, 1, 1177-1237.

Holmes, G. (1939). The cerebellum of man. Brain, 62, 1-30.

Ito, M. (1984). The cerebellum and neural control. New York: Raven Press.

Ito, M. (1990). A new physiological concept on cerebellum. Revue Neurologique (Paris), 146, 564-569.

Ivry, R. B., & Keele, S. W. (1989). Timing functions of the cerebellum. Journal of Cognitive Neuroscience, 1, 136-152.

Jenkins, I. H., Brooks, D. J., Nixon, P. D., Frackowiak, R. S. J., & Passingham, R. E. (1994). Motor sequence learning - a study with Positron Emission Tomography. Journal of Neuroscience, 14, 3775-90.

Jobard, J., Crivello F., and Tzourio-Mazoyer, N (2003). Evaluation of the dual route theory of reading: a metanalysis of 35 neuroimaging studies. Neuroimage in press

Krupa, D. J., Thompson, J. K., & Thompson, R. F. (1993). Localization of a memory trace in the mammalian brain. Science, 260, 989-991.

Leiner, H. C., Leiner, A. L., & Dow, R. S. (1989). Reappraising the cerebellum: what does the hindbrain contribute to the forebrain. Behavioural Neuroscience, 103, 998-1008.

Leiner, H. C., Leiner, A. L., & Dow, R. S. (1991). The human cerebro-cerebellar system: Its computing, cognitive, and language skills. Behav Brain Res, 44, 113 - 128.

Leiner, H. C., Leiner, A. L., & Dow, R. S. (1993). Cognitive and language functions of the human cerebellum. Trends in Neuroscience, 16, 444-447.

Levinson, H. N. (1988). The cerebellar-vestibular basis of learning disabilities in children, adolescents and adults: Hypothesis and study. American Psychiatric Association Annual Meeting New Research Session (1987, Chicago, Illinois). Perceptual and Motor Skills, 67(3), 983-1006.

Levinson, H. N. (1990). The diagnostic value of cerebellar-vestibular tests in detecting learning disabilities, dyslexia, and Attention Deficit Disorder. Perceptual and Motor Skills, 71(1), 67-82.

Malm J, Kristensen B, Karlsson T, Carlberg B, Fagerlund M, and Olsson T. Cognitive impairment in young adults with infratentorial infarcts. Neurology, 51: 433-440, 1998.

Mathiak, K., Hetrich, I., Grodd W, and Ackermann, H. (2002), Cerebellum and speech perception: a functional magnetic resonance imaging study. J. Cogn. Neurosci. 14, 902–912

Moe-Nilssen R, Helbostad JL, Talcott JB, Toennessen FE(2003) Balance and gait in children with dyslexia Experimental Brain Research, 150, 2237-244

Moores, E., Nicolson, R., & Fawcett, A. J. (2003). Attention deficits in dyslexia: evidence for an automatisation deficit? European Journal of Cognitive Psychology, 15(3), 321-348

Moretti, R., Bava, A., Torre, P., Antonello, R. M., & Cazzato, G. (2002). Reading errors in patients with cerebellar vermis lesions. J Neurol, 249(4), 461-468.

Morrison, F. J., & Manis, F. R. (1983). Cognitive processes in reading disability: a critique and proposal. In C. J. Brainerd & M. Pressley (Eds.), Progress in Cognitive Development Research, . New York: Springer-Verlag.

Morton, J., & Frith, U. (1995). Causal modelling: A structural approach to developmental psychopathology. In D. Cicchetti & C. D.J. (Eds.), Manual of Developmental Psychopa-thology, (Vol. 2, pp. 274-298). New York: Wiley.

Nicolson, R. I., & Fawcett, A. J. (1990). Automaticity: A new framework for dyslexia re-search? Cognition, 35(2), 159-182.

Nicolson, R. I., & Fawcett, A. J. (1994). Reaction Times and Dyslexia. Quarterly Journal of Experimental Psychology, 47A, 29-48.

Nicolson, R. I., & Fawcett, A. J. (1995a). Balance, phonological skill and dyslexia: Towards the Dyslexia Early Screening Test. Dyslexia Review, 7, 8-11.

Nicolson, R. I., & Fawcett, A. J. (1995b). Dyslexia is more than a phonological disability. Dyslexia: An international journal of research and practice, 1, 19-37.

Nicolson, R. I., & Fawcett, A. J. (1999). Developmental Dyslexia: The role of the cerebellum. Dyslexia: An International Journal of Research and Practice, 5, 155-177.

Nicolson, R. I., Fawcett, A. J., & Dean, P. (1995). Time-estimation deficits in developmental dyslexia - evidence for cerebellar involvement. Proceedings of the Royal Society of London Series B-Biological Sciences, 259, 43-47.

Passingham, R. E. (1975). Changes in the size and organization of the brain in man and his ancestors. Brain Behaviour and Evolution, 11, 73-90.

Rae, C., Lee, M. A., Dixon, R. M., Blamire, A. M., Thompson, C. H., Styles, P., Talcott, J., Richardson, A. J., & Stein, J. F. (1998). Metabolic abnormalities in developmental dyslexia detected by H-1 magnetic resonance spectroscopy. Lancet, 351, 1849-1852.

Rae, C., Harasty, J. A., Dzendrowskyj, T. E., Talcott, J. B., Simpson, J. M., Blamire, A. M., Dixon, R. M., Lee, M. A., Thompson, C. H., Styles, P., Richardson, A. J., & Stein, J. F. (2002). Cerebellar morphology in developmental dyslexia. Neuropsychologia, 40(8), 1285-1292.

Ramus, F, Pidgeon, E., and Frith, U. (2003a) The relationship between motor control and phonology in dyslexic children. Journal of Child Psychology and Psychiatry and al-lied disciplines, 54, 712-722.

Ramus, F. (2003b). Developmental dyslexia: specific phonological deficit or general sensori-motor dysfunction? Current Opinion in Neurobiology, 13, 212-218

Seidenberg, M. S. (1993). Connectionist models and cognitive theory. Psychological Science, 4, 228-235.

Silver, L. B. (1987). The 'magic cure': A review of the current controverisal approaches for treating learning disabilities. Journal of Learning Disabilities, 20, 498-505.

Silveri, M. C., & Misciagna, S. (2000). Language, memory, and the cerebellum. Journal of Neurolinguistics, 13(2-3), 129-143.

Snowling, M., J, Gallagher, A., Frith, U. (2003). Family risk of dyslexia is continuous: Indi-vidual differences in the precursors of reading skill Child development, 74 (2): 358-373.

Snowling, M., & Hulme, C. (1994). The development of phonological skills. Philosophical Transactions of the Royal Society of London Series B-Biological Sciences, 346, 21-27.

Stanovich, K. E. (1988). Explaining the differences between the dyslexic and the garden-variety poor reader: The phonological-core variable-difference model. Journal of Learning Disabilities, 21, 590-612.

Stein, J., & Walsh, V. (1997). To see but not to read; The magnocellular theory of dyslexia. Trends in Neurosciences, 20, 147-152.

Stein, J. F., & Glickstein, M. (1992). Role of the cerebellum in visual guidance of movement. Physiological Reviews, 72, 972-1017.

Tallal, P., Miller, S., & Fitch, R. H. (1993). Neurobiological Basis of Speech: A Case for the Preeminence of Temporal Processing. Annals of the New York Academy of Sciences., 682, 27-47.

Thach, W. T. (1996). On the specific role of the cerebellum in motor learning and cognition: Clues from PET activation and lesion studies in man. Behavioural and Brain Sciences, 19, 411-431.

Thomson, M, (1984). Developmental dyslexia: Its nature, assessment and remediation. London: Edward Arnold.

Turkeltaub, P. E., Eden, G. F. Jones, K. M. and Zeffiro, T. A. (2002) Meta-analysis of the functional neuroanatomy of single-word reading: Method and validation. Neuroimage 16, 765-780.

Vellutino, F. R. (1979). Dyslexia: Theory and research. Cambridge, MA: MIT Press.

Vicari, S., Marotta, L., Menghini, D., Molinari, M., & Petrosini, L. (2003). Implicit learning deficit in children with developmental dyslexia. Neuropsychologia, 41(1), 108-114

Wimmer H, Mayringer H, Raberger T (1999) Reading and dual-task balancing: Evidence against the automatization deficit explanation of developmental dyslexia Journal of Learning Disabilities, 32:473-478

West, T. G. (1991). In the Mind's Eye: Visual thinkers, gifted people with learning difficulties, computer images, and the ironies of creativity Buffalo NY: Prometheus Books.

Wolf, M., & Bowers, P. G. (1999). The double-deficit hypothesis for the developmental dys-lexias. Journal of Educational Psychology, 91, 415-438.

Publicado

2017-10-31

Número

Sección

ESPECIAL: DISLEXIA